Chronic beryllium disease: T cell recognition of a metal presented by HLA-DP

AP Fontenot, LS Newman, BL Kotzin - Clinical Immunology, 2001 - Elsevier
Beryllium (atomic number 4, atomic weight 9.02) is characterized by a low density, high
melting point, and high stiffness to weight ratio. Because of these properties, it continues to
be utilized in the aerospace, ceramics, electronics, and defense industries. Exposure to
beryllium in the form of the metal, metal oxide, or metal alloy continues to be a major public
health concern, and approximately 800,000 individuals are currently at risk for developing
chronic beryllium disease (CBD)(1). This disorder is estimated to develop in 2 to 16% of …