Cytokine production by T cells infiltrating in the eye of uveitis patients
M Sakaguchi, S Sugita, K Sagawa, K Itoh… - Japanese journal of …, 1998 - Elsevier
The capacity of T cells to produce cytokines was investigated using T-cell clones (TCCs)
established from infiltrating cells in the aqueous humor (AH) or peripheral blood
mononuclear cells (PBMC) of patients with Vogt-Koyanagi-Harada (VKH) disease or
sarcoidosis. The cytokines produced and tested in the study were interleukin (IL)-1α, IL-6, IL-
8, interferon (IFN)-γ, tumor necrosis factor (TNF)-α, and granulocyte monocyte colony
stimulating factor (GM-CSF). All TCCs (n= 9) from AH of VKH patients spontaneously …
established from infiltrating cells in the aqueous humor (AH) or peripheral blood
mononuclear cells (PBMC) of patients with Vogt-Koyanagi-Harada (VKH) disease or
sarcoidosis. The cytokines produced and tested in the study were interleukin (IL)-1α, IL-6, IL-
8, interferon (IFN)-γ, tumor necrosis factor (TNF)-α, and granulocyte monocyte colony
stimulating factor (GM-CSF). All TCCs (n= 9) from AH of VKH patients spontaneously …