Adrenergic changes due to pertussis: insulin, glucose and free fatty acids
IIA Tabachnik, A Gulbenkian - European Journal of Pharmacology, 1969 - Elsevier
IIA Tabachnik, A Gulbenkian
European Journal of Pharmacology, 1969•ElsevierPertussis sensitization increases plasma insulin (IRI) levels and also facilitates insulin
release by isoproterenol, norepinephrine, phenylephrine, and theophylline. Further,
pertussis reverses epinephrine-induced insulin suppression. The elevated IRI levels are
attenuated generally by a β-adrenergic receptor blocker, MJ-1999, and in some instances
an α-adrenergic receptor blocker, phenoxybenzamine. Thus, pertussis appears to enhance
the β-agonist responsiveness insofar as insulin is concerned. Pertussis Glucose Adrenergic …
release by isoproterenol, norepinephrine, phenylephrine, and theophylline. Further,
pertussis reverses epinephrine-induced insulin suppression. The elevated IRI levels are
attenuated generally by a β-adrenergic receptor blocker, MJ-1999, and in some instances
an α-adrenergic receptor blocker, phenoxybenzamine. Thus, pertussis appears to enhance
the β-agonist responsiveness insofar as insulin is concerned. Pertussis Glucose Adrenergic …
Abstract
Pertussis sensitization increases plasma insulin (IRI) levels and also facilitates insulin release by isoproterenol, norepinephrine, phenylephrine, and theophylline. Further, pertussis reverses epinephrine-induced insulin suppression. The elevated IRI levels are attenuated generally by a β-adrenergic receptor blocker, MJ-1999, and in some instances an α-adrenergic receptor blocker, phenoxybenzamine. Thus, pertussis appears to enhance the β-agonist responsiveness insofar as insulin is concerned.
PertussisGlucoseAdrenergicInsulinFree fatty acids
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