Background: Recent research demonstrated that vitamin D, apart from calcium-related
actions, has antiproliferative, prodifferentiative and immunomodulatory activities. Objective:
To determine whether actinic keratoses may benefit from the antiproliferative and
prodifferentiative effects of topical vitamin D. Materials and Methods: The study was an
investigator-blinded, half-side comparison trial. Patients applied calcipotriol cream to one
side and Ultrabase® cream as placebo to the other side of the scalp and/or face for 12 …