Humoral rejection in cardiac transplantation: risk factors, hemodynamic consequences and relationship to transplant coronary artery disease
PJ Michaels, ML Espejo, J Kobashigawa… - The Journal of heart and …, 2003 - Elsevier
BACKGROUND: Acute cellular rejection is the mechanism of most immune-related injury in
cardiac transplant recipients. However, antibody-mediated humoral rejection (HR) has also
been implicated as an important clinical entity following orthotopic heart transplantation.
Humoral rejection has been reported to play a role in graft dysfunction in the early post-
transplant period, and to be a risk factor for the development of transplant coronary artery
disease. Some involved in transplantation pathology doubt the existence of clinically …
cardiac transplant recipients. However, antibody-mediated humoral rejection (HR) has also
been implicated as an important clinical entity following orthotopic heart transplantation.
Humoral rejection has been reported to play a role in graft dysfunction in the early post-
transplant period, and to be a risk factor for the development of transplant coronary artery
disease. Some involved in transplantation pathology doubt the existence of clinically …