The ability of white and brown adipose tissue to efficiently take up long-chain fatty acids is
key to their physiological functions in energy storage and thermogenesis, respectively.
Several approaches have been taken to determine uptake rates by cultured cells and
primary adipocytes including radio-and fluorescently labeled fatty acids. In addition, the
recent description of activatable bioluminescent fatty acids has opened the possibility for
expanding these in vitro approaches to real-time monitoring of fatty acid uptake kinetics by …