[CITATION][C] Demethylase FTO promotes neuropathic pain development via regulating the m6A methylation levels of CXCR3
SF Wu, Y Wang, QC Zhao - Acta Biochimica Polonica, 2022 - ojs.ptbioch.edu.pl
Objective: Neuropathic pain (NPP) is an indirect or direct pain caused by somatic sensory
nervous system dysfunction or primary injury, which is considered to be one of the most
serious public health problems. This study aimed to investigate the role of adiposity-
associated protein (FTO) in NPP. Materials and Methods: Sciatic nerve injury (SNI) treatment
was performed to establish an NPP model in vivo. The qRT-PCR and western blot assays
were conducted to measure the relative mRNA and protein expressions. Additionally, the …
nervous system dysfunction or primary injury, which is considered to be one of the most
serious public health problems. This study aimed to investigate the role of adiposity-
associated protein (FTO) in NPP. Materials and Methods: Sciatic nerve injury (SNI) treatment
was performed to establish an NPP model in vivo. The qRT-PCR and western blot assays
were conducted to measure the relative mRNA and protein expressions. Additionally, the …