Defining the actual incidence and prevalence of mosaicism in human blastocysts still
remains a difficult task. The small amount of evidence generated by animal and human
studies does not support the existence of mechanisms involved in developmental arrest,
clonal depletion, or aneuploidy rescue for abnormal cells in euploid/aneuploid embryos
during preimplantation development. However, studies in humans are mainly descriptive
and lack functional evidence. Understanding the biological mechanisms that beset …