[HTML][HTML] Pre‐transplant IFN‐γ ELISPOTs are associated with post‐transplant renal function in African American renal transplant recipients
JJ Augustine, DS Siu, MJ Clemente, JA Schulak… - American journal of …, 2005 - Elsevier
Final crossmatch testing is routinely used to assess the risk of antibody‐mediated graft
injury/rejection post‐transplant. Analogously, we postulated that quantitative measurements
of anti‐donor effector/memory T cells pre‐transplant would independently assess post‐
transplant risk. To address this hypothesis, we determined the frequencies of pre‐transplant,
donor‐specific interferon‐γ (IFN‐γ) enzyme‐linked immunosorbent spots (ELISPOTs) and
correlated the results with post‐transplant outcomes in 37 African American recipients of …
injury/rejection post‐transplant. Analogously, we postulated that quantitative measurements
of anti‐donor effector/memory T cells pre‐transplant would independently assess post‐
transplant risk. To address this hypothesis, we determined the frequencies of pre‐transplant,
donor‐specific interferon‐γ (IFN‐γ) enzyme‐linked immunosorbent spots (ELISPOTs) and
correlated the results with post‐transplant outcomes in 37 African American recipients of …